leukemia is a type of blood cancer that originates in the bone marrow and leads to the overproduction of abnormal white blood cells. these cells do not function properly and can crowd out healthy cells, affecting the body's ability to fight infection and carry oxygen. leukemia is classified mainly by how quickly it progresses ('acute' or 'chronic') and the type of blood cell affected (lymphocytic or myeloid).
the exact cause of leukemia is not known, but factors that may increase the risk include genetic disorders, exposure to certain chemicals or radiation, smoking, and a family history of the disease. some types of leukemia are also associated with previous cancer treatment or certain genetic syndromes.
symptoms of leukemia can be vague and include fatigue, fever, frequent infections, easy bruising or bleeding, weight loss, swollen lymph nodes, and night sweats. since these symptoms can resemble those of more common illnesses, leukemia can be challenging to diagnose early.
diagnosis typically involves blood tests to look for abnormal levels of white or red blood cells or platelets. bone marrow biopsy, where a sample of marrow is taken for examination, is often necessary to confirm the diagnosis and determine the specific type of leukemia.
treatment for leukemia varies depending on the type and stage of the disease and can include chemotherapy, radiation therapy, targeted therapy, immunotherapy, and in some cases, stem cell transplantation.
ongoing research is focused on understanding the genetic and molecular mechanisms of leukemia and developing new, more effective treatments. trials of new drugs and treatment combinations are continually being conducted, offering hope for improved outcomes.
early detection and advances in treatment have significantly improved the prognosis for many people with leukemia, especially in children, who have higher rates of recovery.