as for treatment, she says there has been great progress in the use of a class of drugs called biologics, which target cell systems. “these drugs can basically target those specific signals that are going wrong. so, in inflammatory arthritis, which is autoimmune, your body is incorrectly attacking its own tissues, and these new drugs can turn off those signals.”
however, the news isn’t so good for osteoarthritis. “unfortunately, we have no drugs that change or target osteoarthritis.” she does say, however, there is ongoing research into disease-modifying osteoarthritis drugs. and scientists are understanding more about this type of arthritis, that it is not a “wear-and-tear disease” but something else going on inside the body. “understanding that better is helping us look for new drugs that can either prevent the cartilage from degrading or help it regenerate.”
like just about every other area of medicine, arthritis researchers believe artificial intelligence could play a role. “it’s being used more and more to look at different models that can help either predict people’s likely trajectory with arthritis, how we can learn from these models, and what predictors will help how somebody will likely fare, or respond to a particular drug or treatment approach. we’re currently investing in a pediatric arthritis study, essentially categorizing kids based on their genetic profile and using ai to help map out how these kids’ respond to certain medications, which will therefore inform future treatment decisions.”