“we found that all combinations of an ophthalmic condition and a systemic condition were associated with an increased risk of dementia,” researchers said. “this risk was greater than that associated with an ophthalmic or a systemic condition only, suggesting that there might be an additive effect of ophthalmic and systemic conditions on the development of dementia. underlying mechanisms are unclear, but impairment of multiple organs than a single is more likely to enlarge the risk of dementia.”
the observational study had a few limitations, notably the self-reported nature of eye issues, which can result in an underestimated prevalence. it is also possible that some of the data researchers relied upon, including death records, may not have documented all cases of dementia. also, in some instances, it is possible that the dementia discovered during follow-up appeared before any ophthalmic issues.
the findings were still significant, however, and underline the potential risks revealed by vision-related problems. “individuals with both ophthalmic and systemic conditions are at higher risk of dementia compared with those with an ophthalmic or systemic condition only,” researchers said. “newly developed hypertension, diabetes, stroke, heart disease and depression mediated the association between cataract/ diabetes-related eye disease and dementia.”
dave yasvinski is a writer with
healthing.ca