the first study,
published in the journal circulation: heart failure
, was the largest to explore the issue to date and only one to examine toxicology data from donors at the time of admission to hospital. the research, which examined more than 23,000 adult heart transplants, found the survival rate of recipients was comparable regardless of whether or not donors used illicit drugs prior to death. opioids, cocaine, methamphetamine, alcohol, barbiturates and amphetamines were among the substances detected in the urine of donors, with some testing positive for five or more substances.
“we thought that illicit drugs like cocaine or methamphetamine, which can lead to heart attacks, would prove to be dangerous,” said david a. baran, lead study author of the study and system director for advanced heart failure and transplantation at sentara heart hospital in norfolk, virginia. “however, we were wrong. we should not reject a heart from a donor just because they used one or more illicit drugs.”
the second study,
published in the journal of the american heart association
, encouraged the acceptance of hearts from donors who used drugs or had hepatitis c prior to death.
“we hope that patients who are awaiting transplants are encouraged to accept hearts from donors who had hepatitis c or who died due to a drug overdose, if their health care team finds the donor heart to be an appropriate match,” said ravi dhingra, lead author of the study and medical director of the heart failure and transplant program and associate professor of medicine at the university of wisconsin-madison.